Emerging Concepts in Ribosome Structure, Biogenesis, and Function

Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview on all parts in this process. The book begins with an introduction to the ribosome factory, its origin and its evolution of translation. Sections discuss subunits, RNA, protein components, and its emergence as a frontier research area for translational potential in cancer and other diseases. In addition, the book explores current developments in ribosome research, including the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes.

This book provides the emerging research on ribosomes, their biogenesis, and other important topics on structure and function. Therefore, it will serve as a resourceful introduction for both new researchers and those engaged in interdisciplinary ribosomal research.

Provides an overview of ribosome biogenesis and examines its involvement in cell transformation and cancerous growth
Covers disorders related to the ribosome (ribosomopathies)
Explains the significance of ribosome dysfunction in human diseases
Includes commonly used methods to study ribosomes, such as polysome preparation, RNA analysis and proteomics, CryoEM, and Cell-free assays, along with proper illustrations

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